Pulmonary hemodynamics in chronic obstructive pulmonary disease (Three decades of study in the Republic of Moldova)

Abstract

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide. COPD is frequently associated with comorbidities, the most common complication being pulmonary hypertension and subsequent right heart failure. The prevalence of pulmonary hypertension and the pathophysiological processes of its installation in patients with COPD remain insufficiently studied, although it is known that its share increases with the severity of COPD, and its rate has been reported ranging from 20% to 90%. in the article, the author summarizes the notorious international discoveries and local contributions in this field, elucidating the opportunities, challenges and perspectives of studying the problem. Multiple investigations conducted in the last three decades by local researchers have deepened the knowledge of the pathophysiology, clinic, diagnosis, treatment and prophylaxis of pulmonary hemodynamic and cardiac function disorders in patients with COPD. Further investigations in this area are needed