Diagnosis and treatment characteristics of mucinous ovarian tumors

Authors

  • Rotaru Tudor Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” Catedra oncologie
  • Ludmila Rotaru
  • Mocan Daniela Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” Catedra oncologie
  • Balan Nicu Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” Catedra oncologie

DOI:

https://doi.org/10.52692/1857-0011.2021.2-70.16

Keywords:

mucinous ovarian tumor, differential diagnosis, tumor marker, surgical treatment

Abstract

Diagnosis and treatment characteristics of mucinous ovarian tumors. Introduction: Ovarian tumors occupy a special place in gynecological pathology due to their great diversity, diagnostic difficulties, specifying their evolutionary nature, establishing the prognosis and treatment. Ovarian mucinous tumors are a group of rare formations, with a cell of as yet undefined origin, but with an apparent progression from benign to borderline and carcinoma. The treatment of a benign ovarian tumor is surgical. Material and methods. The research in question was performed on a group of 50 patients, who were treated in the gynecology department of the IMSP Oncological Institute of the Republic of Moldova, with the diagnosis of mucinous ovarian tumors. Results. The study analyzed data on the diagnosis and treatment of mucinous ovarian tumors. The clinical diagnosis showed a unilateral ovarian involvement in 41 cases (82%) compared to the bilateral one registered in 9 patients (18%). All tumors were large and irregularly shaped. In the case of laboratory diagnosis in assessing the benign or malignant tumor potential, the tumor marker CA-125 was performed, in 41 patients the index was within the norm range from 0-35U / ml and only in 9 cases were there insignificant increases of 50-100U / ml. Ultrasonographic diagnosis is an important method in detecting mucinous ovarian tumors. The treatment of patients is surgical and, depending on the appearance of the tumor intraoperatively and age, they had a radical or less radical character. Conclusions. The most common clinical signs were fullness in the pelvis, dysuria, pain in the lumbar or sacral region. As usual, the mucous ovarian tumors are large. The CA-125 tumor marker was in most cases within the normal range. Imaging investigations are informative and some of them applied to all patients in the study. Endoscopic diagnostic methods are less informative in mucinous ovarian tumors due to bulky formations and the risk of effusion of the mucin into the abdominal cavity

Published

2021-06-25