Central giant cell granuloma in the mandibula: clinical, radiological and histopathological study in 2 clinical cases

Authors

  • Ţîbîrnă Gheorghe IMSP Centru Stomatologic Municipal de Copii
  • Railean Silvia IMSP Centru Stomatologic Municipal de Copii
  • Porosencov Egor IMSP Centru Stomatologic Municipal de Copii
  • Porosencova Tatiana Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”
  • Lupan Roman IMSP Centru Stomatologic Municipal de Copii

DOI:

https://doi.org/10.52692/1857-0011.2021.2-70.18

Keywords:

central giant cell granuloma, clinical aspects, radiological aspects, histopathological aspects

Abstract

Central giant cell granuloma (CGCG) is a benign and proliferative lesion of the jaw, with an unknown etiology. It is widely considered to be a neoplastic lesion. The current etiology of GCGC is still unclear, although local inflammation, bleeding, and trauma have been suggested. The biological behavior of CGCG of the jaw varies from resting to aggressive with destructive expansion. The incidence in the general population is very low, and patients are generally under 30 years of age females. In this study, we report two cases of GCGC in 8-year-old and 13 year old girls treated surgically

Author Biographies

Ţîbîrnă Gheorghe, IMSP Centru Stomatologic Municipal de Copii

acad. prof. univ;Catedra de Chirurgie oro-maxilo-facială pediatrică și pedodonție „Ion Lupan”

Railean Silvia, IMSP Centru Stomatologic Municipal de Copii

dr. șt. med., conf. univ;Catedra de Chirurgie oro-maxilo-facială pediatrică și pedodonție „Ion Lupan”

Porosencov Egor, IMSP Centru Stomatologic Municipal de Copii

asist. univ

Porosencova Tatiana, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”

dr. șt. med., conf. univ;Catedra de propedeutică stomatologică „Pavel Godoroja”

Lupan Roman, IMSP Centru Stomatologic Municipal de Copii

asist. univ;Catedra de Chirurgie oro-maxilo-facială pediatrică și pedodonție „Ion Lupan”

References

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Kruse-Lösler B., Diallo R., Gaertner C. et al. Central giant cell granuloma of the jaws: A clinical, radiologic, and histopathologic study of 26 cases. Oral Surgery, Oral Med. Oral Pathol. Oral Radiol. Endodontology. 2006; 101(3): 346–354.

Published

2021-09-25

Issue

Section

Research Article