Inefficacy of Sildenafil treatment of idiopathic pulmonary hypertension.

Authors

  • Constantin MARTINIUC IMSP Institute of Phthisiopneumology "Chiril Draganiuc", Chisinau, Republic Of Moldova
  • Serghei PISARENCO IMSP Institute of Phthisiopneumology "Chiril Draganiuc", Chisinau, Republic Of Moldova
  • Iurie SIMIONICA IMSP Institute of Phthisiopneumology "Chiril Draganiuc", Chisinau, Republic Of Moldova

DOI:

https://doi.org/10.52692/1857-0011.2021.3-71.49

Keywords:

idiopathic pulmonary hypertension, sildenafil, pulmonary haemodynamics

Abstract

There were studied effects of phosphodiesterase inhibitor Sildenafil on clinical and functional status in young patientwith severe primary pulmonary hypertension. Sildenafil was applicated in dose of 50-100 mg daily for 12 weeks, clinicaland functional status were estimated initial and after every month of treatment. The retrospective analysis do not detectedany positive dynamics in all estimated parameters, this phenomena may be explained by individual patient refractivity onthis group of medicine.

Author Biographies

Constantin MARTINIUC, IMSP Institute of Phthisiopneumology "Chiril Draganiuc", Chisinau, Republic Of Moldova

dr. hab. șt. med., conf. cerc.

Serghei PISARENCO, IMSP Institute of Phthisiopneumology "Chiril Draganiuc", Chisinau, Republic Of Moldova

dr. hab. șt. med., șef laborator

Iurie SIMIONICA, IMSP Institute of Phthisiopneumology "Chiril Draganiuc", Chisinau, Republic Of Moldova

dr. șt. med., conf. cerc

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Published

2021-11-17

Issue

Section

Research Article