Intestinal lipase inhibitors in the treatment of metabolic syndrome in children.


  • MATRAGUNA Nelea IMSP Institutul de Cardiologie , IMSP Spitalul Clinic Municipal de Copii „Valentin Ignatenco‟
  • TUREA Tatiana Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu‟



metabolic syndrome, orlistat, obesity, treatment, children, adolescents


Obesity and overweight among children and adolescents are accepted worldwide as a chronic multifactorial disorder, with a significant increase in annual prevalence. Abdominal obesity in association with other metabolic risk factors such as hypertension, high cholesterol and triglycerides, as well as low HDL cholesterol are grouped into a syndrome defined as„Reaven syndrome” or „metabolic syndrome”. MetS is often associated with cardiovascular and diabetic risk in children and also with liver damage. Current strategies addressed for the treatment of obesity and metabolic syndrome in children include adequate nutrition, combating sedentary lifestyle, drug therapy, which are used alone, or in combination. These measures are taken to reduce overweight, dyslipidemia, high blood pressure and insulin resistance in children and adolescents.

Author Biographies

MATRAGUNA Nelea, IMSP Institutul de Cardiologie , IMSP Spitalul Clinic Municipal de Copii „Valentin Ignatenco‟

dr. hab. în șt. med., conf. cercetător

TUREA Tatiana, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu‟



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