Acute pulmonary embolism associated with acute thrombosis of the deep venous system.


  • Doina RANGA Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”
  • Natalia CAPROȘ Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”
  • Hristiana CAPROSH Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”



Pulmonary embolism, acute thrombosis, deep venous system


The purpose of the study was to present a clinical case of pulmonary embolism in a young patient of 26 years, with a brief review of the literature. The particularity of the presented case with the pulmonary embolism was the association with the acute thrombosis of the deep venous system venous system on background of combined oral contraceptives use.

Author Biographies

Doina RANGA, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”

doctoral student Year. I

Natalia CAPROȘ, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”

dr. hab. in sht. med., Assoc. univ.

Hristiana CAPROSH, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”

dr. in sht. med., Assoc. univ.


Stavros V Konstantinides, Guy Meyer, Cecilia Becattini, et al. The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC), EHJ, 41, 4, 2020:543–603, https://.org/10.1093/eurheartj/ehz405

Grosu A., David L., Cuzor T., et al. Tromembolismul pulmonar. PCN-148. 2020, 56pps.

Rogers MA, Levine DA, Blumberg N, et al. Triggers of hospitalization for venous thromboembolism. Circulation 2012;125(17): 2092–2099..

Ku GH, White RH, Chew HK, et al. Venous thromboembolism in patients with acute leukemia: incidence, risk factors, and effect on survival. Blood 2009;113(17):3911–3917

Timp JF, Braekkan SK, Versteeg HH, Cannegieter SC. Epidemiology of cancerassociated venous thrombosis. Blood 2013;122(10):1712–1723.

Gussoni G, Frasson S, La Regina Met al. Threemonth mortality rate and clinical predictors in patients with venous thromboembolism and cancer. Findings from the RIETE registry. Thromb Res 2013;131(1):24–30.

Khorana AA, Kuderer NM, Culakova E, et al. Development and validation of a predictive model for chemotherapyassociated thrombosis. Blood 2008;111(10):4902–4907.

Piazza G, Goldhaber SZ. Venous thromboembolism and atherothrombosis: an integrated approach. Circulation 2010;121(19):2146–2150

Piazza G, Goldhaber SZ, Lessard DM, et al. Venous thromboembolism in patients with symptomatic atherosclerosis. Thromb Haemost 2011;106(6):1095–1102.

Enga KF, Braekkan SK, Hansen-Krone IJ, et al. Cigarette smoking and the risk of venous thromboembolism: the Tromso Study. J Thromb Haemost 2012;10(10):2068–2074.

Wattanakit K, Lutsey PL, Bell EJ, et al. Association between cardiovascular disease risk factors and occurrence of venous thromboembolism. A time-dependent analysis. Thromb Haemost 2012;108(3):508–515.

Sørensen HT, Horvath-Puho E, Lash TL, et al. Heart disease may be a risk factor for pulmonary embolism without peripheral deep venous thrombosis. Circulation 2011;124(13):1435–1441.

Pomp ER, Lenselink AM, Rosendaal FR, Doggen CJ. Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study. J Thromb Haemost 2008;6(4):632–637.

Henriksson P, Westerlund E, Wallén H, et al. Incidence of pulmonary and venous thromboembolism in pregnancies after in vitro fertilisation: cross sectional study. BMJ 2013;346:e8632

Sweetland S, Beral V, Balkwill A, et al. Venous thromboembolism risk in relation to use of different types of postmenopausal hormone therapy in a large prospective study. J Thromb Haemost 2012;10(11):2277–2286.

Faculty of Sexual & Reproductive Healthcare (FSRH) provided funding to the Clinical Effectiveness Unit (of the FSRH) to assist them in the production of this guideline, Combined Hormonal Contraception (January 2019, amended November 2020).





Research Article