Safety profile of antituberculosis drugs


  • Lucia ȚURCAN IP State University of Medicine and Pharmacy "Nicolae Testemițanu"
  • Lilia PODGURSCHI IP State University of Medicine and Pharmacy "Nicolae Testemițanu"
  • Tatiana RAKOVSKAIA IP State University of Medicine and Pharmacy "Nicolae Testemițanu"
  • Artur SAITOV IP State University of Medicine and Pharmacy "Nicolae Testemițanu"



antituberculosis drugs, side effects, hepatotoxicity, neurotoxicity, isoniazid, rifampicin, linezolid


Studying the safety profile of antituberculosis drugs is a priority for the development of a treatment regimen as efficient as possible and with a high degree of tolerability for patients. The development of side adverse reactions of antituberculosis drugs continues to remain one of the main causes of low compliance or even abandonment of the administered treatment. The detection, reporting and analysis of adverse effects associated with the administration of antituberculosis drugs, both for first-line and second-line drugs, serves as a guarantee of successful treatment.

Author Biographies

Lucia ȚURCAN, IP State University of Medicine and Pharmacy "Nicolae Testemițanu"

Dr. in Med. Sci., Assoc. Prof. Univ.; Department of Pharmacology and clinical pharmacology

Lilia PODGURSCHI, IP State University of Medicine and Pharmacy "Nicolae Testemițanu"

Dr. in Med. Sci., Assoc. Prof. Univ.; Department of Pharmacology and clinical pharmacology

Tatiana RAKOVSKAIA, IP State University of Medicine and Pharmacy "Nicolae Testemițanu"

fourth-year doctoral student, university assistant; Department of Pharmacology and clinical pharmacology

Artur SAITOV, IP State University of Medicine and Pharmacy "Nicolae Testemițanu"

sixth-year student; Department of Pharmacology and clinical pharmacology


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Research Article