Major risks of harmful environmental carcinogenic effects in light industry enterprises
DOI:
https://doi.org/10.52692/1857-0011.2024.1-78.32Keywords:
ircadian light/dark cycle, night shifts, clock genes, neoplastic process, hormone-dependent tissuesAbstract
Synthesis paper revealing fundamental data on the epigenetic determination of the initiation and maintenance of neoplastic processes in the breast tissue of female workers in light industry enterprises. The primary importance of the synchronization of circadian rhythms in the environment and the biorhythms of the biological molecular, cellular and internal tissue clocks is noted. Preventive programs should be based on preventing the desynchronization of neuroendocrine mechanisms involving melatonin and hormone-dependent tissues of the internal environment with circadian light/dark cycles of the external environment. The forced nature of the work activity associated with the development of social jetlag requires the provision of recreation periods after the rotation period.
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