The impact of perinatal antecedents in the achievement of bronchopulmonary dysplasia in premature children

Authors

  • Svetlana SCIUCA State University of Medicine and Pharmacy „Nicolae Testemitanu”; IMSP Mother and Child Institute
  • Mariana CEAHLAU State University of Medicine and Pharmacy „Nicolae Testemitanu”
  • Aliona COTOMAN State University of Medicine and Pharmacy „Nicolae Testemitanu”; IMSP Mother and Child Institute
  • Rodica SELEVESTRU State University of Medicine and Pharmacy „Nicolae Testemitanu”; IMSP Mother and Child Institute

DOI:

https://doi.org/10.52692/1857-0011.2023.2-76.10

Keywords:

bronchopulmonary dysplasia, premature babies, risk factors

Abstract

Bronchopulmonary dysplasia (BPD) - chronic bronchopulmonary disease, determined by multifactorial causes in children born prematurely that evolves with broncho-obstructive syndrome, symptoms of respiratory insufficiency, pneumofibrosis.Methods. An analytical, cohort study of children with BPD was performed. Compared to preterm infants without BPD. Results. The study demonstrated that the gestational age at birth of children with BPD is lower veridically (p<0.00001) with values of 29.14±0.5 weeks compared to the gestational age at birth of children without BPD - 32, 6±0.5 weeks. The birth weight of premature babies with BPD is significantly (p<0.00001) lower (1358.15±85.2 gr) compared to premature babies without BPD (1983.3±109.9 gr). The birth height of premature babies with BPD (38.5±0.8 cm) is significantly lower (p<0.00001) compared to that of children without BPD (43.7±0.8 cm). Head circumference and chest circumference are also smaller in children with BPD. Apgar score in the first minute after birth and over 5 min. of children with BPD is significantly lower (p<0.0001) compared to the values of children without BPD. Conclusions: The study established that the average gestational age under 29.14 weeks, the average birth weight under 1358.15 g, the Apgar score under 5.54/6.46 for children born prematurely are perinatal factors with potential risk in the achievement of bronchopulmonary dysplasia at children born prematurely.

Author Biographies

Svetlana SCIUCA, State University of Medicine and Pharmacy „Nicolae Testemitanu”; IMSP Mother and Child Institute

Memb. Corr. ASM, Prof., Dr. Med. Sci., Dr. Sci. Med.; Department of Pediatrics; Clinic of Pulmonology

Mariana CEAHLAU, State University of Medicine and Pharmacy „Nicolae Testemitanu”

doctoral student, pediatrician.; Department of Pediatrics

Aliona COTOMAN, State University of Medicine and Pharmacy „Nicolae Testemitanu”; IMSP Mother and Child Institute

pediatric pneumologist; Department of Pediatrics; Clinic of Pulmonology

Rodica SELEVESTRU , State University of Medicine and Pharmacy „Nicolae Testemitanu”; IMSP Mother and Child Institute

Assoc. Prof., Dr. Med. Sci.; Department of Pediatrics; Clinic of Pulmonology

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Published

2023-11-24

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Research Article

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