Specificities of childhood tumours and the paediatric oncology service in the context of decentralisation
DOI:
https://doi.org/10.52692/1857-0011.2023.2-76.18Keywords:
опухоли, особенности, педиатрическая онкологическая служба, децентрализация, управление, детиAbstract
Tumors in children have peculiarities of natural development, diagnosis and clinical features, morphological structure, age, sex, pre-selection, etc. In the structure of oncopediting morbidity prevail hemoblasts 58-60%, brain tumors 17- 18%, kidney 7-7.5%, bone 5.0-5.5%, soft tissue sarcomas 4.0-4.5%, thyroid gland tumors 0.8-1.0%, reproductive organs1.0-1.2%, liver - 1.0%, others - 2.5-3.0% [15, 16, 23].Tumors in children occupy the second place in the structure of mortality of children up to 18 years of age. A special place goes to Eving’s sarcoma, Wilms’ tumor, embryonal rhabdomyosarcoma and others [21].The oncology service also has its own particular managerial features, such as having certain criteria and facilities, centres specialising in paediatric oncology, specialists, technical devices, diagnostic and treatment technologies, medical equipment and generic and effective drugs. The service must have onco-pediatric specialists in every region of the Republic of Moldova - north, centre, south and south-east. Interdisciplinary cooperation is needed with family medicine, local specialists and tertiary specialists, as well as with the families of these children, local administrative bodies and the voluntary sector. There is a need for an infrastructure for the paediatric oncology advisory service and interdependence with the Oncology Institute, rehabilitation centres, continuing education centres in hospital and palliative care, and social services.
References
Baudou E, Chaix Y. The value of screening tests in children with neurofibromatosis type 1 (NF1). In: Childs Nerv Syst. 2020 Oct, 36(10), pp. 2311-2319. doi: 10.1007/s00381-020-04711-6.
Bernic I., Petrovici V., Roller V., Curajos A., Gudumac E. Isolated renal hydatid cyst in the primary generation of the larval cyst. În: Moldovan Medical Journal. June 2020, 63(2), p. 5-11.
Boenzi S., Catesini G., Sacchetti E., Tagliaferri F., Dionisi-vici C., Deodato F. Comprehensive-targeted lipidomic analysis in Niemann-Pick C disease. In: Mol Genet Metab. 2021 Dec, 134(4), pp. 337-343. doi: 10.1016/j.ymgme.2021.11.00.
Boscainos P.J., Cousins G.R., Kulshreshtha R., Oliver T.B., Papagelopoulos P. J. Osteoid osteoma. In: Orthopedics. 2013 Oct 1;36(10):792-800. doi: 10.3928/01477447-20130920-10.
Butler E., Ludwig K., Pacenta H.L , Klesse L.J., Watt T.C., Laetsch T.W. Recent progress in the treatment of cancer in children. In: CA Cancer J Clin. 2021 Jul, 71(4), pp. 315-332. doi: 10.3322/caac.21665.
Dimaras H., Dimba E., Gallie B. L. Challenging the global retinoblastoma survival disparity through a collaborative research effort. In: Br J Ophthalmol. 2010, 94(11), pp. 1415-1416. doi: 10.1136/bjo.2009.174136.
Fochtman D. The concept of suffering in children and adolescents with cancer. In: J Pediatr Oncol Nurs. 2006 Mar-Apr, 23(2), pp. 92-102. doi: 10.1177/104345420528587.
Gerali M., Servitzoglou M., Paikopoulou D. et al. Psychological problems in children with cancer in the initial period of treatment. In: Cancer Nurs. 2011 JulAug, 34(4), pp. 269-276. doi: 10.1097/NCC.0b013e3181fa5698.
Grünewald T.G., Alonso M., Avnet S. et al. Sarcoma treatment in the era of molecular medicine. In: EMBO Mol Med. 2020 Nov 6, 12(11), p. e11131. doi: 10.15252/emmm.20191113.
Gudumac E. Chirurgie pediatrică. Chișinău, 2012. 248 p.
Jung K.W., Won Y.J., Hong S., Kong H.J., Lee E.S. Prediction of Cancer Incidence and Mortality in Korea, 2020. In: Cancer Res Treat. 2020 Apr, 52(2), pp. 351-358. doi: 10.4143/crt.2020.203.
Kebudi R., Ozdemir G.N. Secondary Neoplasms in Children Treated for Cancer. In: Curr Pediatr Rev. 2017, 13(1), pp. 34-41. doi: 10.2174/1573396313666 16111423313.
Mereuță I., Tcacenco E., Popușoi E. Aspecte medico-sociale, managerial si clinice ale tumorilor la copii în R. Moldova. In: Congresul I National de oncologie. Chisinau, 2000, p. 9-12.
Mereuță I., Tcacenco E., Vozian I., Rusu L. Managementul în serviciul oncologic pediatru al R. Moldova. In: Congresul I Național de oncologie. Chisinau, 2000, p. 21-22.
Mereuţă I. Aspecte clinice şi metodologice ale dificultăţilor în activitatea medicilor traumatologi-ortopezi, din perspectivele vigilenţei oncologice. Chişinău, 2012, 58 p.
Mereuță I. Tumorile la copii. Managementul clinic al cancerelor ereditate. Chișinău, 2012. 72 p.
Mereuță I., Martalog V. Retinoblastomul. Ghid. Chișinău, 2018. 35 p.
Mereuță I., Țîbîrnă G.H., Fedaș V., Tomșa A. Incidența și mortalitatea prin maladia COVID-19 în Republica Moldova în anul 2020. Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţe medicale (Materialele Conferinţei Știinţifice Naționale cu participare internațională „Chirurgia personalizată la adulți și copii chirurgia viitorului”). 2022, 2(73), p. 138-147. ISSN 1857-0011.
Moberg L,. Fritch J., Westmark D., Mina D.S., Krause C., Bilek L., Acquazzino M. Effect of physical activity on fatigue in childhood cancer survivors: a systematic review. In: Support Care Cancer. 2022 Aug, 30(8), pp. 6441-6449. doi: 10.1007/s00520-022-06960-4
Momani T.G., Hathaway D.K., Mandrell B.N. Factors Affecting Health-Related Quality of Life in Children Undergoing Curative Treatment for Cancer: A Review of the Literature. In: J Pediatr Oncol Nurs. 2016 May-Jun, 33(3), pp. 228-240. doi: 10.1177/1043454215609585.
Mu P.F., Lee M.Y., Sheng C.C., Tung P.C, Huang L.Y., Chen Y.W. The experiences of family members in the year following the diagnosis of a child or adolescent with cancer: a qualitative systematic review. In: JBI Database System Rev Implement Rep. 2015 Jun 12, 13(5), pp. 293-329. doi: 10.11124/jbisrir-2015-169.
Parker L. Children’s cancer in the developing world: where are the girls? In: Pediatr Hematol Oncol. 1998 Mar-Apr,15(2), pp. 99-103. doi: 10.3109/08880019809167223.
Rask O., Nilsson F., Lähteenmäki P. et al. Prospective registration of symptoms and times to diagnosis in children and adolescents with central nervous system tumors: A study of the Swedish Childhood Cancer Registry. In: Pediatr Blood Cancer. 2022 Nov, 69(11), p. e29850. doi: 10.1002/pbc.29850.
Renzi S., Langenberg-Ververgaert K.P.S, Waespe N., Ali S., Bartram J., Michaeli O., Upton J., Cada M. Primary immunodeficiencies and their associated risk of malignancies in children: an overview. In: Eur J Pediatr. 2020 May;179(5):689-697. doi: 10.1007/s00431020-03619-2
Rogers P.C., Barr R.D. The relevance of nutrition to pediatric oncology: A cancer control perspective. In: Pediatr Blood Cancer. 2020 Jun, 67 Suppl 3, p. e28213. doi: 10.1002/pbc.28213.
Ruland C.M., Hamilton G.A., Schjødt-Osmo B. The complexity of symptoms and problems experienced in children with cancer: a review of the literature. In: J Pain Symptom Manage. 2009 Mar, 37(3), pp. 403-18. doi: 10.1016/j.jpainsymman.2008.03.009.
Steliarova-Foucher E., Colombet M., Ries LAG. et al. International incidence of childhood cancer, 2001-10: a population-based registry study. In: Lancet Oncol. 2017 Jun, 18(6), pp. 719-731. doi: 10.1016/S14702045(17)30186-9.
Vozian I. Managementul serviciului oncopediatric in Republica Moldova (actualităţi şi perspective). In: Revista ştiinţifico-practică „Info-Med”. 2012, nr. 1(19), pp. 50-53. ISSN 1810-3936.
Wang J., Zhanghuang C., Tan X., Mi T., Liu J., Jin L., Li M., Zhang Z, He D. A Nomogram for Predicting Cancer-Specific Survival of Osteosarcoma and Ewing’s Sarcoma in Children: A SEER Database Analysis. In: Front Public Health. 2022 Feb 1, 10, p. 837506. doi: 10.3389/fpubh.2022.837506.
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