Clinical forms, detection and diagnosis of tuberculosis in children during the pandemic and postpandemic period of COVID-19
DOI:
https://doi.org/10.52692/1857-0011.2024.2-79.11Keywords:
tuberculosis, COVID-19, children, diagnosis, pandemicAbstract
Clinical forms, detection and diagnosis of tuberculosis in children during the pandemic and post-pandemic period of COVID-19. Introduction. The pandemic caused by COVID-19 has had a major impact on tuberculosis (TB) screening. WHO declared in a. 2022 an 18% decrease in notified TB cases between 2019 and 2020 - from 7.1 to 5.8 million cases and a 20% increase in TB deaths over the next 5 years as a result of the COVID-19 pandemic. The aim of the study. Assessment of the impact of the COVID-19 pandemic on the detection, diagnosis and evolution of TB in children. Material and methods. A retrospective study was carried out which included the analysis of 610 cases of patients aged between 0-18 years, admitted for treatment in the Municipal Clinical Hospital Chisinau between 2019 and 2023. Results. TB predominated in the 0-9 age group. The diagnosis of intrathoracic lymph node TB was established in 68% of cases. Complications were more common in 2023. Conclusion. During the COVID-19 pandemic, a faulty detection of TB is attested.
References
Tuberculoza la copil. Protocol Clinic National. PCN-55. Chișinău, 2023. 217 p.
Migliori GB, Thong PM, Akkerman O, Alffenaar JW et al. Worldwide Effects of Coronavirus Disease Pandemic on Tuberculosis Services. January-April 2020. J Emerg Infect Dis. 2020 Nov;26(11):2709-2712. https://doi.org/10.3201/eid2611.203163.
Migliori GB, Thong PM, Alffenaar JW, Denholm Jet al. Country-specific lockdown measures in response to the COVID-19 pandemic and its impact on tuberculosis control: a global study. J Bras Pneumol. 2022;48(2): e20220087.
Migliori GB, Thong PM, Alffenaar JW, Denholm Jet al. Global Tuberculosis Network. Gauging the impact of the COVID-19 pandemic on tuberculosis services: a global study. Eur Respir J. 2021 Nov 11;58(5):2101786.
McQuaid CF, Vassall A, Cohen T, Fiekert K, White RG. The impact of COVID-19 on TB: a review of the data. Int J Tuberc Lung Dis. 2021 Jun 1;25(6):436-446.
Rodrigues I, Aguiar A, Migliori GB, Duarte R. Impact of the COVID-19 pandemic on tuberculosis services. Pulmonology. 2022 May-Jun;28(3):210-219.
Shah I, Gupta Y. Role of molecular tests for diagnosis of tuberculosis in children. Pediatric Oncall Journal. 2015;12(1)
Silva DR, Mello FCQ, D’Ambrosio L, Centis R, Dalcolmo MP, Migliori GB. Tuberculosis and COVID-19, the new cursed duet: what differs between Brazil and Europe? J Bras Pneumol. 2021 Apr 30;47(2):e20210044.
Systematic screening for active tuberculosis. Principles and recommendations. Geneva: World Health Organization; 2013 (WHO/HTM/TB/2013.04).
The End TB Strategy. Global strategy and targets for tuberculosis prevention, care and control after 2015. Geneva, Switzerland. https://www.aidsdatahub.org/sites/default/files/resource/end-tb-strategy-2015.pdf
Tadolini M, Codecasa LR, García-García JM, Blanc FX, Borisov S et. Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases. Eur Respir J. 2020 Jul 9;56(1):2001398.
WHO consolidated guidelines on tuberculosis. Module 1: prevention – tuberculosis preventive treatment. Geneva: World Health Organization; 2020. https://www.who.int/publications/i/item/9789240002906.
WHO consolidated guidelines on tuberculosis Module 2: Screening – Systematic screening for tuberculosis disease. Geneva: World Health Organization; 2021. https://www.who.int/publications/i/item/9789240022676
World Health Organization. Global tuberculosis report 2022: Geneva, Switzerland, 2021. https://apps.who.int/iris/handle/10665/340256
World Health Organization. Global tuberculosis report 2023: Geneva, Switzerland, 2024. https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2024/
Gupta U, Prakash A, Sachdeva S, Pangtey GS, Khosla A, Aggarwal R, et al. COVID-19 and Tuberculosis: A Meeting of Two Pandemics! J Assoc Physicians India. 2020;68(12):69-72.
Programul Naţional de Răspuns la Tuberculoză pentru anii 2022–2025. https://www.legis.md/cautare/getResults?doc_id=130171&lang=ro
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