Maternal infectious risk factors in intrauterine infection in premature newborn
DOI:
https://doi.org/10.52692/1857-0011.2024.2-79.25Keywords:
intrauterine infection, premature newborn, sepsisAbstract
The article analyzes the influence of various maternal factors during pregnancy and childbirth on the development of intrauterine infection and its severity in the newborn. The study was carried out on a group of 133 premature children from mothers at risk of infection, of which 82 (61,66%) children with intrauterine infections (including 47 (35,34%) children with localized infections (pneumonia) and 35 (26,32%) children with sepsis) and 51 (38,35%) children with infectious risks without their development. The profile of the premature newborn with sepsis in the neonatal period was established, among the maternal clinical and anamnestic criteria being infectious complications during pregnancy (60%), birth complication with premature rupture of the amniotic sac (80%) and chorioamnionitis (12%).
References
Vogel JP, Souza JP, Mori R, Morisaki N, Lumbiganon P, et al., on behalf of the WHO Multicountry Survey on Maternal and Newborn Health Research Network. Maternal complications and perinatal mortality: findings of the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 2014; 121 (Suppl. 1): 76–88.
Sukumaran, A., et al. (2019). Neonatal immune adaptations in response to intrauterine infections. Clinical Infectious Diseases, 69(3), 564-571.
Heath, P. T., & Culver, D. (2022). Perinatal infections and immune responses in neonates. Infectious Disease Clinics of North America, 36(1), 93-110.
Goldenberg, R. L., Culhane, J. F., Iams, J. D., & Romero, R. (2008). Epidemiology and causes of preterm birth. The Lancet, 371(9606), 75-84.
Romero, R., Espinoza, J., & Kusanovic, J. P. (2014). The preterm parturition syndrome. BJOG: An International Journal of Obstetrics & Gynaecology, 121(2), 127-166.
Gomez-Lopez, N., Romero, R., Xu, Y., Leng, Y., Garcia-Flores, V., Miller, D., ... & Hassan, S.S. (2017). Fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications. Seminars in Fetal and Neonatal Medicine, 22(5), 265-277.
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