The effects of glucocorticosteroids and their specific usage in athletes.

Authors

  • Ina POGONEA Nicolae Testemițanu State University of Medicine and Pharmacy
  • Maria MIHALACHI-ANGHEL Nicolae Testemițanu State University of Medicine and Pharmacy
  • Tatiana TIMERCAN Nicolae Testemițanu State University of Medicine and Pharmacy; National Anti-Doping Agency
  • Artiom JUCOV Nicolae Testemițanu State University of Medicine and Pharmacy; National Anti-Doping Agency
  • Silvia STRATULAT Nicolae Testemițanu State University of Medicine and Pharmacy
  • Alisa TABIRTA Nicolae Testemițanu State University of Medicine and Pharmacy
  • Victoria CHIHAI Nicolae Testemițanu State University of Medicine and Pharmacy
  • Gheorghe STEFANET National Center for Sports Medicine "Atletmed"
  • Liviu MEREACRI Nicolae Testemițanu State University of Medicine and Pharmacy

DOI:

https://doi.org/10.52692/1857-0011.2024.2-79.42

Keywords:

Glucocorticosteroids, physical performance, prohibited substances, fatigue, euphoria, sports regulations

Abstract

Introduction. It is well known that, since ancient times, athletes have used various prohibited substances to enhance
their physical performance. Glucocorticosteroids, hormonal preparations synthesized by the adrenal glands and their
synthetic analogues, are used for their analgesic and anti-inflammatory effects, which can mask the sensation of fatigue.
Additionally, these hormones can produce a mildly euphoric state, which may distort the athlete’s true performance.
Materials and Methods. The analysis is based on a review of existing literature and studies concerning the use of
glucocorticosteroids in sports. The effects of these steroids on physical performance and the impact of their administration.
Results. The use of glucocorticosteroids, regardless of the route of administration, is prohibited during sporting
competitions. Observed effects include masking the sensation of fatigue and influencing the athlete’s euphoric state, thus
providing a distorted view of true performance. Local injections, including intra-articular and peritendinous injections,
are included in the list of banned substances.
Conclusions. Glucocorticosteroids can significantly impact athletic performance by masking fatigue and inducing an
euphoric state. Their use in competitions is strictly regulated. It is essential for athletes and support personnel to be aware
of these regulations to ensure the integrity of sporting events.

Author Biographies

Ina POGONEA, Nicolae Testemițanu State University of Medicine and Pharmacy

PhD in medical sciences, Associate Professor

Maria MIHALACHI-ANGHEL , Nicolae Testemițanu State University of Medicine and Pharmacy

University Assistant

Tatiana TIMERCAN, Nicolae Testemițanu State University of Medicine and Pharmacy; National Anti-Doping Agency

PhD in Medical Sciences, Associate Professor

Artiom JUCOV, Nicolae Testemițanu State University of Medicine and Pharmacy; National Anti-Doping Agency

PhD in Medical Sciences, Associate Professor

Silvia STRATULAT , Nicolae Testemițanu State University of Medicine and Pharmacy

Doctor of Medical Sciences, Associate Professor

Alisa TABIRTA, Nicolae Testemițanu State University of Medicine and Pharmacy

Doctor of Medical Sciences, Associate Professor

Victoria CHIHAI , Nicolae Testemițanu State University of Medicine and Pharmacy

PhD in Medical Sciences, Associate Professor

Gheorghe STEFANET, National Center for Sports Medicine "Atletmed"

sports doctor

Liviu MEREACRI, Nicolae Testemițanu State University of Medicine and Pharmacy

student

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Published

2025-04-18

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