Spinal Arterio-Venous Malformations: Clinical Case and Literature Review

Authors

  • Diana ZETU-BUCIUSHCAN Nicolae Testemițanu State University of Medicine and Pharmacy; Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Elena MANOLE Nicolae Testemițanu State University of Medicine and Pharmacy; Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Anastasia LEVCA Nicolae Testemițanu State University of Medicine and Pharmacy; Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Galina TIMCIUC Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Oxana GROSU Nicolae Testemițanu State University of Medicine and Pharmacy
  • Ion PREGUZA Institute of Neurology and Neurosurgery "Diomid Gherman"

DOI:

https://doi.org/10.52692/1857-0011.2024.3-80.38

Keywords:

malformation, aretrio-venous, spinal

Abstract

Vascular malformations of the spinal cord, namely arteriovenous malformations (AVMs) and fistulas (AVFs), account for less than 5% of intraspinal pathology and cause severe and progressive symptoms. Ultimately, this rarity and heterogeneity of AVMs leads to very diverse treatment options that depend on AVM classification. They represent a developmental abnormality of the vascular system, which is a tangle of poorly formed blood vessels in which the feeding arteries are directly connected to a network of venous drainage without any intervening capillary system. They can occur anywhere in the body, but of major importance are the cerebral and spinal, having a major risk of causing serious neurological damage and can present diagnostic and therapeutic challenges for the radiological and surgical teams. The evaluation of these injuries can be further complicated by the lack of a universally accepted classification scheme. Early diagnosis improves outcomes because patients can benefit from early intervention.

Author Biographies

Diana ZETU-BUCIUSHCAN, Nicolae Testemițanu State University of Medicine and Pharmacy; Institute of Neurology and Neurosurgery "Diomid Gherman"

resident physician

Elena MANOLE , Nicolae Testemițanu State University of Medicine and Pharmacy; Institute of Neurology and Neurosurgery "Diomid Gherman"

univ. assoc. prof., PhD med. sci.

Anastasia LEVCA , Nicolae Testemițanu State University of Medicine and Pharmacy; Institute of Neurology and Neurosurgery "Diomid Gherman"

resident physician

Galina TIMCIUC, Institute of Neurology and Neurosurgery "Diomid Gherman"

imaging specialist

Oxana GROSU, Nicolae Testemițanu State University of Medicine and Pharmacy

PhD med. sci., senior researcher

Ion PREGUZA , Institute of Neurology and Neurosurgery "Diomid Gherman"

neurosurgeon

References

Patchana T, Savla P, Taka T M, et al., Spinal Arteriovenous Malformation: Case Report and Review of the Literature. Cureus., (November 21, 2020); 12(11): e11614.

Lad SP, Santarelli JG, Patil CG, Steinberg GK, Boakye M, National trends in spinal arteriovenous malformations. Neurosurg Focus, 2009, 26:1-5.

G. Esposito et al. (eds.), Trends in Cerebrovascular Surgery and Interventions, Acta Neurochirurgica Supplement 132, The Author(s), 2021; 129.

Kona MP, Buch K, Singh J, Rohatgi S., Spinal Vascular Shunts: A Patterned Approach. AJNR Am J Neuroradiol., 2021 Dec; 42(12):2110-2118.

Gross BA, Du R., Spinal juvenile (type III) extradural- intradural arteriovenous malformations. J Neurosurg Spine - CrossRef Medline, 2014; 20:452–58.

Vuong SM, Jeong WJ, Morales H, et al., Vascular diseases of the spinal cord: infarction, hemorrhage, and venous congestive myelopathy. Semin Ultrasound CT MR, CrossRef Medline, 2016; 37:466–81.

Singh R, Lucke-Wold B, Gyure K, et al., A review of vascular abnormalities of the spine. Ann Vasc Med Res Medline, 2016; 3:1045.

Takai K., Spinal arteriovenous shunts: angio- architecture and historical changes in classification. Neurol Med Chir (Tokyo), CrossRef Medline, 2017; 57:356–65.

Gross BA, Du R., Spinal pial (type IV) arteriovenous fistulae: a systematic pooled analysis of demographics, hemorrhage risk, and treatment results. Neurosurgery, 2013; 73:141–51.

Kalani MA, Choudhri O, Gibbs IC, et al., Stereotactic radiosurgery for intramedullary spinal arteriovenous malformations. J Clin Neurosci, 2016; 29:162–67.

Singh B, Behari S, Jaiswal AK, et al., Spinal arteriovenous malformations: is surgery indicated?. Asian J Neurosurg, 2016; 11:134.

Sorenson T, Giordan E, Cannizzaro D, et al., Surgical ligation of spinal dural arteriovenous fistula. Acta Neurochir (Wien),2018; 160:191–94.

Goyal A, Cesare J, Lu VM, et al., Outcomes following surgical versus endovascular treatment of spinal dural arteriovenous fistula: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry, 2019;90:1139–46.

Samonenko YM, Shchehlov DV, Sviridyuk OE, et al., Endovascular and microsurgical treatment for spinal arteriovenous malformations: our experience. Endovasc Neuroradiol, 2019; 27:32–40.

Sasamori T, Hida K, Yano S, et al., Long-term outcomes after surgical and endovascular treatment of spinal dural arteriovenous fistulae. Eur Spine J., 2016; 25:748–54.

Kular S, Tse G, Budu A, et al., Transarterial CT angiography for surgical planning of spinal dural arteriovenous fistula. Br J Radiol, 2020; 93:20200020.

Mathur S, Bharatha A, Huynh TJ, et al., Comparison of time-resolved and first-pass contrast-enhanced MR angiography in pretherapeutic evaluation of spinal dural arteriovenous fistulas. AJNR Am J Neuroradiol, 2017; 38:206–12.

Marini TJ, Chughtai K, Nuffer Z, et al., Blood finds a way: pictorial review of thoracic collateral vessels. Insights Imaging, 2019;10:63–68.

Published

2025-09-09

Issue

Section

Research Article

Categories