THE COURSE OF RESISTANT PULMONARY TUBERCULOSIS COMBINATED WITH HIV-INFECTION AMONG ADULTS
DOI:
https://doi.org/10.52692/1857-0011.2025.3-83.04Keywords:
HIV/AIDS/TB, chemoresistant pulmonary tuberculosisAbstract
The researched group was 1.5 times dominated by male patients (42: 68.8%), over female (19: 31.2%), while the majority of people were aged 31 to 50 years. 9.8% (6) of patients with chemoresistant pulmonary TB were hospitalized in serious condition. The average number of bed-days in hospital was (61.7 ± 4.5). 16 (26.2%) patients with chemoresistant TB died in the hospital.
Our research shows that among patients with CR-PTB/HIV, rifampicin (R) resistance was 2 times more common than resistance to combination HRZE and Pre-XDR (32.8% vs. 16.4%, P < 0.05). Resistance to combination HRZ was the least common (1.4%). In some cases, they showed resistance to new anti-TB drugs (Bdg and Dlm). Disseminated PTB was 2.4 times more often diagnosed than miliary TB, and infiltrative PTB was 4.0 times more likely among CR-PTB/HIV.
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