Risk factors and clinical manifestations in patients with pulmonary infections caused by nontuberculous mycobacteria.

Abstract

The incidence of pulmonary infection with NTM increases with age and varies significantly between countries. NTMs are opportunistic pathogens that cause disease, especially in immunocompromised patients or with pre-existing lung disease. In 2021-2024, 22 patients with pulmonary mycobacteriosis were admitted to the MCHP. The majority of patients were men, MAC predominated, followed by M. kansasii. Risk factors included the medical-biological, HIV- infection, respiratory system pathology, harmful habits, hystory of tuberculosis (TB). Age over 51 years old had 50% of the patients. History of TB had 1/3 of the patients. Among the associated diseases the respiratory system diseases predominated (86,4%): COPD, bronchiectasis, neoplastic processes, othres. Diagnosis was estableshed in the period up 2 weeeks from hospitalisation in 68,8% cases. Clinical picture were presented by bronchopulmonary, toxico-infection syndromes.