Acute pulmonary edema – critical mortality factor in patients with chronic kidney disease.

Authors

  • Iuliana SMOLENSCHI Nicolae Testemițanu State University of Medicine and Pharmacy
  • Sergiu MATCOVSCHI Nicolae Testemițanu State University of Medicine and Pharmacy
  • Lilia VLASOV Nicolae Testemițanu State University of Medicine and Pharmacy
  • Natalia CAPROSH Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova

DOI:

https://doi.org/10.52692/1857-0011.2025.3-83.18

Keywords:

Pulmonary edema, chronic kidney disease, mortality

Abstract

Acute pulmonary edema (APE) is a common complication in patients with chronic kidney disease (CKD). This study aims to analyze the incidence of APE as the main cause of death in patients with CKD. We evaluated 55 patients with CKD including clinical examinations, laboratory data and paraclinical investigations, and the data were statistically processed. The results revealed that acute pulmonary edema is the main cause of death among patients with CKD, observed in 58% of patients. The differences in mortality between sexes suggest an increased risk for men, dependent of age or other known risk factors, which requires a personalized approach to care according to sex.

Author Biographies

Iuliana SMOLENSCHI, Nicolae Testemițanu State University of Medicine and Pharmacy

PhD Student

Sergiu MATCOVSCHI, Nicolae Testemițanu State University of Medicine and Pharmacy

Doctor Habilitated in Medical Sciences, University Professor

Lilia VLASOV, Nicolae Testemițanu State University of Medicine and Pharmacy

Doctor of Medical Sciences, University Associate Professor

Natalia CAPROSH, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova

Doctor of Medical Sciences, University Associate Professor

References

Rao M, Bandela PV, Bandi VK, et al. Pulmonary function tests in patients with chronic kidney disease: a cross-sectional study. Indian J Nephrol. 2020;30(4):270–276.

Douvris A, Chan CT. Pulmonary edema in hemodialysis: mechanisms and management. Semin Dial. 2017;30(3):230–35.

Francis, A., Harhay, M.N., Ong, A.C.M. et al. Chronic kidney disease and the global public health agenda: an international consensus. Nat Rev Nephrol 20, 473– 485 (2024).

Plantinga L., King M., Tahsin M. et al. Burden and correlates of readmissions related to pulmonary edema in US hemodialysis patients: a cohort study. Nephrology Dialysis Transplantation, Volume 33, Issue 7, July 2018, Pages 1215–1223.

Hasegawa, S., Nakano, S., Tanno, J. et al. Effect of cardiovascular risk factors and time of hospital presentation on mortality of maintenance hemodialysis patients presenting with acute pulmonary edema. Ren Replace Ther 3, 8, 2017.

Jimnaz PA, Kharim AA. Acute pulmonary oedema in chronic dialysis patients, causes, clinical course and outcome admitted into emergency department. Int J Adv Med 2017;4:1541- 6.

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Published

2026-04-29

Issue

Vol. 83 No. 3 (2025): Medical Sciences

Section

Research Article

Categories

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Copyright (c) 2026 Bulletin of the Academy of Sciences of Moldova. Medical Sciences

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