Multidimensional approach and mortality risk stratification scores in chronic obstructive pulmonary disease.

Authors

  • Ana POPA Муниципальная клиническая больница «Святая Троица»
  • Tatiana HARGHEL Муниципальная клиническая больница «Святая Троица»; Государственный университет медицины и фармации «Николае Тестемицану»
  • Natalia CAPROSH Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova
  • Sergiu MATCOVSCHI Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova

DOI:

https://doi.org/10.52692/1857-0011.2025.3-83.19

Keywords:

COPD, mortality, comorbidities, CODEX, BNP

Abstract

Chronic obstructive pulmonary disease (COPD) is associated with systemic manifestations and frequent cardiovascular comorbidities. These comorbidities significantly affect patient prognosis. We prospectively evaluated 426 hospitalized patients with COPD exacerbations using spirometry, CAT and mMRC questionnaires, comorbidity indices, and biomarkers. Independent predictors of mortality included elevated BNP, reduced FEV1, and higher CODEX score. Multidimensional assessment provides superior prognostic stratification compared to spirometry alone.

Author Biographies

Ana POPA, Муниципальная клиническая больница «Святая Троица»

доктор медицинских наук, научный сотрудник

Tatiana HARGHEL, Муниципальная клиническая больница «Святая Троица»; Государственный университет медицины и фармации «Николае Тестемицану»

PhD Student

Natalia CAPROSH, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova

Doctor of Medical Sciences, University Professor

Sergiu MATCOVSCHI, Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova

Doctor of Medical Sciences, University Professor

References

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Published

2026-04-29

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Section

Research Article

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