News in the diagnosis of gastric precancerous lesions.
DOI:
https://doi.org/10.52692/1857-0011.2021.3-71.34Keywords:
chronic atrophic gastritis, gastric intestinal metaplasia, dysplasia of the epithelium of the gastric mucosa, endoscopic examination, morphological examination, serological examination, Helicobacter pyloriAbstract
Introduction: Detection and close monitoring of patients with precancerous lesions - chronic atrophic gastritis (GCA), gastric intestinal metaplasia (MIG) and gastric mucosal epithelial dysplasia (DEMG) is a priority to increase early detection and, implicitly, decrease mortality and mortality. by gastric cancer (GC). The aim of the present study is to develop a narrative synthesis of contemporary studies on GCA diagnostic methods. Material and methods: Eligible studies were searched in the PubMed, Hinari, SpringerLink and Scopus (Elsevier) databases during the years 2000-2020. Results: Out of 575 articles addressing the topic of precancerous lesions, 59 articles were qualified representative for the materials published on the topic of this synthesis article. Conclusions: There are two main methodological approaches for GCA evaluation: non-invasive serological examination using gastric function markers and invasive examination, which requires histological analysis of biopsy samples taken during upper digestive endoscopy, the latter being the „gold standard” for diagnosis.References
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