Новизна в диагностике предраковыx поражений желудка.

Авторы

  • Адриана БОТЯЗУ ИП государственный университет медицины и фармации им. Николае Тестемицану, Республика Молдова
  • Эльмира АНТОЧИ ИП государственный университет медицины и фармации им. Николае Тестемицану, Республика Молдова
  • Чезар ЗАГОРЯНУ Государственный университет медицины и фармации ИП "Николае Тестемицану", Республика Молдова
  • Мурдар Мухамад АГБАРИЯ Государственный университет медицины и фармации ИП "Николае Тестемицану", Республика Молдова
  • Николай Бодруг Государственный университет медицины и фармации ИП "Николае Тестемицану", Республика Молдова

DOI:

https://doi.org/10.52692/1857-0011.2021.3-71.34

Ключевые слова:

хронический атрофический гастрит, кишечная метаплазия желудка, дисплазия эпителия слизистой оболочки желудка, эндоскопическое исследование, морфологическое исследование, серологическое исследование, Helicobacter pylori

Аннотация

Введение: Выявление и тщательный мониторинг пациентов с предраковыми поражениями - хроническим атрофическим гастритом (ХАГ), кишечной метаплазией желудка (КМЗ) и эпителиальной дисплазией слизистой оболочки желудка (ДСОЖ) является приоритетом для повышения раннего выявления и, косвенно, снижения смертности и смертности рак желудка (РЖ). Целью данного исследования является разработка нарративного синтеза современных исследований методов диагностики ХАГ. Материалы и методы. В течение 2000-2020 годов проводилось изучение подходящих исследований в базах данных PubMed, Hinari, SpringerLink и Scopus (Elsevier). Результаты: Из 575--ти статей, посвященных теме предраковых поражений, 59 статей были квалифицированным представителем материалов, опубликованных по теме данной сводной статьи. Выводы: существует два основных методологических подхода к оценке GCA: неинвазивное серологическое исследование с использованием маркеров функции желудка и инвазивное исследование, которое требует гистологического анализа биоптатов, взятых во время эндоскопии верхних отделов пищеварения, последнее является «золотым стандартом» для диагностики.

Биографии авторов

Адриана БОТЯЗУ, ИП государственный университет медицины и фармации им. Николае Тестемицану, Республика Молдова

dr.șt.med., asist.univ.,

Эльмира АНТОЧИ, ИП государственный университет медицины и фармации им. Николае Тестемицану, Республика Молдова

doctorand

Чезар ЗАГОРЯНУ, Государственный университет медицины и фармации ИП "Николае Тестемицану", Республика Молдова

student anul III

Мурдар Мухамад АГБАРИЯ, Государственный университет медицины и фармации ИП "Николае Тестемицану", Республика Молдова

student anul VI

Николай Бодруг, Государственный университет медицины и фармации ИП "Николае Тестемицану", Республика Молдова

dr.hab.șt.med., prof.univ.

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Опубликован

2021-11-17

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Научная статья