Updates in screening for tuberculosis. Review of guidelines.


  • Evelina LESNIC "Nicolae Testemitanu" State University of Medicine and Pharmacy
  • Alina MALIC "Nicolae Testemitanu" State University of Medicine and Pharmacy
  • Alexandru CORLĂTEANU "Nicolae Testemitanu" State University of Medicine and Pharmacy




screening, tuberculosis, management


The aim of the study was to evaluate the current guidelines and methodological recommendations on the detection of suspects and methods of diagnosis of tuberculosis in order to identify the need to update them.

Material and methodology: a review of the literature consisting in the evaluation of the electronic sources published in PubMed and the HINARI health literature collection, as well as the paper publications, were evaluated. The results were grouped and systematized according to the level of scientific evidence.
Results: the development of new guidelines and the updating of those already in use has a major importance for the standardization of TB screening and diagnostic procedures, and the annual review is one of the key principles of the management of the screening actions.

Author Biographies

Evelina LESNIC, "Nicolae Testemitanu" State University of Medicine and Pharmacy

dr. în șt. med.,

Alina MALIC, "Nicolae Testemitanu" State University of Medicine and Pharmacy

dr. în șt. med.,

Alexandru CORLĂTEANU, "Nicolae Testemitanu" State University of Medicine and Pharmacy

dr. hab. în șt. med.


World Health Organization. Tuberculosis Report, 2020. https://www.who.int/publications/i/item/9789240037021

Ministerul Sănătății. Protocolul Clinic Național Tuberculoza la adult, 2020. https://msmps.gov.md/wp-content/uploads/2021/02/PCN-123-Tuberculoza_la_adult.pdf

WHO. Chest radiograpghy in tuberculosis detection. Summary of current WHO recommendations and guidance on programmatic approaches. 2016. https://apps.who.int/iris/handle/10665/252424

WHO. Consolidated guidelines on tuberculosis: module 2: systematic screening for tuberculosis disease. 2021. https://www.who.int/publications/i/item/9789240022676

WHO. Systematic screening for active tuberculosis: an operational guide. 2016. https://www.who.int/publications/i/item/9789241549172

Ustian A., Cernenco N, Lesnic E. Particularitățile tuberculozei pulmonare în funcție de metoda depistării. În: Sănătate publică, Economie şi Management în Medicină. Chişinău, 2015, vol.59, nr 2, p. 48-52. ISSN 1729-8687.

GLI model TB diagnostic algorithms. Revised June 2018. http://www.stoptb.org/wg/gli/assets/documents/GLI_algorithms.pdf

WHO. International Standards for Tuberculosis Care, Edition 3. TB CARE I, The Hague, 2014. https://www.who.int/tb/publications/ISTC_3rdEd.pdf

Centre for Disease Control. Core Curriculum on Tuberculosis: What the Clinician Should Know. Sixth Edition, 2013. CDC. https://www.cdc.gov/tb/education/corecurr/pdf/corecurr_all.pdf

Centre for Disease Control. TB screening and testing of health care personnel. https://www.cdc.gov/tb/topic/testing/healthcareworkers.htm

Curdu V. Diagnosticul microbiologic al tuberculozei. Ghid. Chișinău, 2012, https://www.researchgate.net/profile/Valeriu-Crudu/publication/299584273_Diagnosticul_microbiologic_al_tuberculozei/links/5700d8f508aea6b77469bc37/Diagnosticulmicrobiologic-al-tuberculozei.pdf.

The PIH Guide to the Medical Management of Multidrug-Resistant Tuberculosis. 2nd edition. Partners in health, 2013. https://parthealth.3cdn.net/b0233c0e1e4088e07b_unm6vyf2f.pdf





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