Lymphangiomas in the head and neck region in children
DOI:
https://doi.org/10.52692/1857-0011.2023.2-76.07Keywords:
pediatric lymphatic malformations, Sclerotherapy, Systematic review, Siroloim, Vascular anomaly, Lymphangiomatosis, Paediatric mass, Rapamycin, Lymphatic malformationAbstract
Back ground. The treatment of lymphangiomas in children is a challenge because of slow but insidious growth, as well as because of infiltrative growth. In the region of the head and neck in children the problem of solving is a very difficult moment. On the one hand, the damage to the organs located in this region, on the other hand, the cosmetic problem and the growth of the child. Surgical treatment is the mainstay in the treatment of lymphangiomas in children, but the only method does not solve the problem in question. The goal. Evaluation of methods of treatment of lymphangiomas in children. Materials and methods. The study was carried out on the bibliographic basis and in particular the treatment of lymphangiomas in children in the head and neck region with pharmaceutical preparations. The ones reported in the bibliography were Sirolimus and Bleomycin. Several parameters were examined in both groups - age, sex, location of neoplasm, treatment and complications following treatment Results. More severe adverse effects were found in the group of children who received Serolim compared to those who were treated by sclerotherapy with Blaomycin. Conclusion Safety is a major concern in the treatment of vascular anomalies in children. The use of Sirolimus is indicated in cases of danger to the child’s life. Further research with randomized controlled trials is needed to establish the benefits of off-label use of sirolimus in these complex pathological processes.
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