Pulmonary embolism in postmenopausal women: a case report
DOI:
https://doi.org/10.52692/1857-0011.2024.3-80.39Keywords:
Pulmonary thromboembolism, womenAbstract
This study presents the case of a 73-year-old female patient with multiple cardiovascular comorbidities. The case’s particularities include nonspecific symptoms, delayed presentation, and a dramatic outcome despite the implementation of complex treatment, including anticoagulation. The literature review focused on the following aspects: the incidence and severity of PE in women versus men, the role of comorbidities in influencing PE risk, and differences in thrombolysis usage.
References
Robert-Ebadi H, Le Gal G, Carrier M, et al. Differences in clinical presentation of pulmonary embolism in women and men. J Thromb Haemost. 2010 Apr;8(4):693-8.
Ramos, A., Flores M., Benzant I. et al. Pulmonary embolism in Spain: Differences between men and women. European Respiratory Journal. 2015; 20(1):546.
Tanabe Y., Yamamoto T., Murata T. et al. Gender Differences Among Patients With Acute Pulmonary Embolism. Am J Cardiol. 2018 Sep 15;122(6):1079- 1084.
Yoshikawa Y, Yamashita Y, Morimoto T. et al. COMMAND VTE Registry Investigators. Sex Differences in Clinical Characteristics and Outcomes of Patients With Venous Thromboembolism - From the COMMAND VTE Registry. Circ J. 2019 Jun 25;83(7):1581-1589.
Ciarambino, T.; Crispino, P.; Para, O.; Giordano, M. Gender Medicine: A New Possible Frontiers of Venous Thromboembolism. Stresses. 2023, 3, 167-181.
Keller K., Rappold L., Gerhold-Ay A. et al. Sex- specific differences in pulmonary embolism. Thromb Res. 2019 Jun;178:173-181.
de Moreuil C, Le Mao R, Le Moigne E. et al. Long-term recurrence risk after a first venous thromboembolism in men and women under 50 years old: A French prospective cohort. Eur J Intern Med. 2021 Feb;84:24- 31.
Pribish AM, Beyer SE, Krawisz AK., et al. Sex differences in presentation, management, and outcomes among patients hospitalized with acute pulmonary embolism. Vasc Med. 2020 Dec;25(6):541-548.
Giustozzi M, Valerio L, Agnelli G, et al. Sex-specific differences in the presentation, clinical course, and quality of life of patients with acute venous thromboembolism according to baseline risk factors. Insights from the PREFER in VTE. Eur J Intern Med. 2021 Jun;88:43-51.
Tian H, Zhang Y, Liu J, et al. CURES investigators. Sex disparities of clinical manifestations in acute pulmonary embolism and predictive value for in- hospital mortality: Insights from CURES. Thromb Res. 2024 Nov;243:109146.
Newman J, Bruno E, Allen S, et al. The influence of patient sex on pulmonary embolism evaluation, treatment modality, and outcomes. Vasc Med. 2024 Sep 12:1358863X241281872.
Downloads
Published
License
Copyright (c) 2025 Bulletin of the Academy of Sciences of Moldova. Medical Sciences

This work is licensed under a Creative Commons Attribution 4.0 International License.