What is hidden after Acute Coronary Syndrome?

Authors

DOI:

https://doi.org/10.52692/1857-0011.2025.2-82.16

Keywords:

Acute coronary syndrome, Takotsubo syndrome, multimodal imaging

Abstract

Stress (“Tako-Tsubo”) cardiomyopathy or Takotsubo syndrome (TTS), is characterized by acute but rapidly reversible LV systolic dysfunction in the absence of atherosclerotic coronary artery disease, triggered by strong psychological, physical or iatrogenic stress. Takotsubo syndrome is a complex and still poorly recognized heart disease with a wide spectrum of possible clinical presentations. Despite its reversibility, it is associated with serious adverse in-hospital events and high complication rates during follow-up. Multimodal imaging is helpful for establishing the diagnosis, guiding therapy, and stratifying prognosis of TTS patients in both the acute and post-acute phase. This article describes the clinical case of a 67 - year - old woman who, after a strong emotional stress, presented with clinical manifestations of ACS. Following laboratory tests and investigations (ECG, Echocardiography, Chest X-ray, Coronary angiography, Ventriculography) the diagnosis of Takotsubo Syndrome was established. Based on treatment with beta-adrenoblockers, anticoagulants, dual antiplatelet therapy (Aspirin+Clopidogrel), nitrates, statins, metabolic drugs (Mildronate), the patient’s condition improved, with the recovery of left ventricular systolic function.

Author Biographies

Silvia FILIMON , Nicolae Testemițanu State University of Medicine and Pharmacy

Dr. habil. in Medical Sciences, Research Associate Professor

Liviu GRIB, Nicolae Testemițanu State University of Medicine and Pharmacy

Dr. habil. in Medical Sciences, University Professor

Alexandra GREJDIERU, Nicolae Testemițanu State University of Medicine and Pharmacy

PhD in Medical Sciences, Associate Professor

Elena SAMOHVALOV, Nicolae Testemițanu State University of Medicine and Pharmacy

PhD in Medical Sciences, Associate Professor

Andreea FILIMON, “Grigore T. Popa” University of Medicine and Pharmacy

masterand

Nicolae LUTICA , “Holy Trinity” Municipal Clinical Hospital

Interventional cardiologist

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Published

2026-03-26

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Research Article

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