LOD efficiency and pronouncement factors in the treatment of polycystic ovary syndrome infertility.
DOI:
https://doi.org/10.52692/1857-0011.2025.3-83.22Keywords:
polycystic ovary syndrome, laparoscopic ovarian drilling, prognostic factors, infertility treatment, prognosisAbstract
Purpose. To establish the prognostic factors of positive LOD response in the treatment of infertility in polycystic ovary syndrome.
Materials and methods. 138 clinical cases of patients selected according to the Rotterdam criteria for polycystic ovary syndrome, hospitalized in the Department of Aseptic Gynecology No. 1 of the Municipal Clinical Hospital No. 1 in Chisinau city, were analyzed.
Results. Age is an important prognostic criterion. The success rate is significantly higher in patients up to 35 years of age (p=0.79, χ²=11.738). Obesity with a BMI >30 kg/m2 represented a lower ovulation rate (p < 0.01) compared to those with a BMI (26 – 29) - 18%. In patients with T > 4.5nmol/l, the ovulation rate is – 13% (p < 0.05) lower than the ovulation rate - 20.2% in women with slightly elevated T 2.6-4.4nmol/l. Patients with normal T < 2.6 represented a higher success rate (p<0.01) (ovulation rate – 42.3%) compared to the other groups. The LH level has a significant impact: patients who responded after LOD had pretreatment LH concentrations ≥ 10IU/l (p=0.29, χ²=20.862, p<0.001) than those who had lower LH < 10IU/l, before LOD.
Conclusions. The success rate of treatment with visual impairment (LOD) correlates with the following criteria: age, duration of infertility, BMI, LH, T.
References
Назаренко Т.А. Синдром поликистозных яичников: современные подходы к диагностике и лечению бесплодия – М.: МЕДпресс-информ, 2005. – 208 с.
Геворкян М.А. Восстановление фертильности после оперативной лапароскопии у женщин с синдромом поликистозных яичников /М.А. Геворкян, И.Б. Манухин, М.А. Царькова // Проблемы репродукции. - 2002. - Т.6, №2. - С. 19-22.
Ada H. „Polycystic ovarian syndrome 1; PCOS1”. OMIM //McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine. Retrieved 15 November 2011.
Azziz R., Woods K.S., Reyna R., Key T.J., Knochenhauer E.S., Yildiz B.O. The prevalence and features of the polycystic ovary syndrome in an unselected population //J. Clin. Endocrinol. Metab 2004, (89):2745-2749
Adashi E.Y., Rock J.A., Guzick D., Wentz A.C., JONES G.S. Fertility following bilateral ovarian wedge resection: a critical analysis of 90 consecutive cases of the polycystic ovary syndrome. Fertil. Steril. Vol.35, 1981, p. 320 – 5
Alien W.M., Woolf R.B. Medullary resection of the ovaries in the Stein – Leventhal syndrome.J. Obstet Gynecol.Vol. 77, 1959, p.826-34
Armar N.A., Lachelin G.C. Laparascopic ovarian diathermy: an effective treatment for anti-oestrogen resistant anovulatory infertility in women with the polycystic ovary syndrome. Br. J. Obstet. Gynaecol. Vol.100, 1993, p. 161 – 164.
Asada H., Kishi I., Kaseda S. et al., Laparascopic treatment of women polysystic ovary syn-drome with the holium: YAG laser. Fertil Steril. 2002; 77:852-3
Amer S.A., Li T.C., Cook I.D. Repeated laparascopic ovarian diathermy is effective in women with anovulatory infertility duet o polysystic ovary syndrome. Fertil Steril. 2003; 79:1211-5
Amer S.A., Li T.C., Cooke I.D. Laparoscopic ovarian diathermy in women with polycystic ovarian syndrome: a retrospective study on the influence of the amount of energy used on the outcome. Human Reproduction. vol.17, no.4 pp.1046-1051, 2002.
Apridonidze T., Essah P.A., Iuorno M.J., Nestler J.E. Prevalence and characteristics of the me-tabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2005,(90):1929-1935.
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