Respiratory recovery in post-COVID-19 syndrome.

Authors

  • Paraschiva POSTOLACHE Universitatea de Medicină și Farmacie ”Grigore T. Popa”
  • Vlad-Florin OIEGAR Grigore T. Popa University of Medicine and Pharmacy
  • Constantin GHIMUSH Grigore T. Popa University of Medicine and Pharmacy

DOI:

https://doi.org/10.52692/1857-0011.2025.3-83.37

Keywords:

post-COVID-19 syndrome, pulmonary rehabilitation, physical exercise, telerehabilitation, post COVID-19 interstitial lung disease

Abstract

Post-COVID-19 syndrome represents a complex clinical entity characterized by the persistence of symptoms for at least two months after the initial SARS-CoV-2 infection. This multisystemic condition involves respiratory, cardiovascular, neurological, and psychological dysfunctions, generating a significant impact on patients’ quality of life. The present article examines the pathogenic mechanisms involved, including immune dysregulation, viral persistence, intestinal dysbiosis, and endothelial dysfunction. Diagnostic modalities and symptom severity assessment are also presented, with emphasis on the importance of respiratory function tests, exercise capacity evaluation, and quality of life assessment. Pulmonary rehabilitation, as the cornerstone in the management of post-COVID-19 syndrome, is detailed, highlighting the role of physical training, breathing techniques, and multidisciplinary support. In addition, specific aspects of post- COVID-19 interstitial lung disease (PC-ILD) and related therapeutic strategies are discussed. The article highlights the need for an individualized approach and careful monitoring of patients to optimize outcomes and improve prognosis.

Author Biographies

Paraschiva POSTOLACHE, Universitatea de Medicină și Farmacie ”Grigore T. Popa”

University Professor, Habilitated Doctor

Vlad-Florin OIEGAR, Grigore T. Popa University of Medicine and Pharmacy

PhD student

Constantin GHIMUSH, Grigore T. Popa University of Medicine and Pharmacy

докторант

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Published

2026-04-29

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Research Article

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