TUBERCULOZA PEDIATRICĂ ÎN RAPORT CU SISTEMUL IMUN
DOI:
https://doi.org/10.52692/1857-0011.2022.3-74.04Cuvinte cheie:
tuberculoză, status imun, copiiRezumat
Pediatric tuberculosis (TB) is of primary genesis - it develops as a result of the child’s first contact with a source of contagious infection. In most cases in children the infection remains latent, and under certain conditions evolves into TB disease. The immune status is the decisive factor in this process. In this article we want to analyze the impact of immunocompetence in the response process of the child’s macroorganism to infection with Mycobacterium tuberculosis .
Referințe
Boisson-dupuis S, Bustamante J, El-Baghdadi J, Camcioglu Y, Parvaneh N, El AS, et al. Inherited and acquired immunodeficiencies underlying tuberculosis in childhood. In: Immunol Rev. 2015;264(1):103–120.
Botnaru V., Brocovschii V., Cemîrtan S., Țîmbală D. Elemente de imunologie. Chișinău, 2020, 332p.
Bousfiha A, Jeddane L, Picard C, Al-Herz W, Ailal F, Chatila T, et al. Human inborn errors of immunity: 2019 update of the IUIS Phenotypical Classification. In: J Clin Immunol. 2020;40(1):66–81.
Bustamante J, Boisson-dupuis S, Abel L, Casanova J-L. Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity. In: Semin Immunol. 2014;26(6):454–470.
Carreto-Binaghi LE, Juárez E, Guzmán-Beltrán S, et al. Immunological evaluation for personalized interventions in children with tuberculosis: should it be routinely performed? In: J Immunol Res. 2020.
Casanova JL. Severe infectious diseases of childhood as monogenic inborn errors of immunity. In: Proc. Natl. Acad. Sci. USA. 2015;112:E7128–7137.
S. de Martino Maurizio., Galli Luisa,; Chiappini Elena. Reflections on the immunology of tuberculosis: will we ever unravel the skein?. In: BMC Infectious Diseases, 2014; 14(1 Supplement).
Dreesman A, Corbière V, Dirix V, et al. Age-Stratified T cell responses in children infected with Mycobacterium tuberculosis. In: Front Immunol. 2017; 8: 1059.
Ernst J.D. The immunological life cycle of tuberculosis. In: Nature Rev. 2012;14:581–591.
Ferluga J., Yasmin H., Al-Ahdal MN., Bhakta S., Kishore U. Natural and Trained Innate Immunity against Mycobacterium tuberculosis. In: Immunobiology, 2020, May; 225(3):151951.
Glanzmann B., Uren C., de Villiers N., et al. Primary immunodeficiency diseases in a tuberculosis endemic region: challenges and opportunities. In: Genes and Immunity. 2019;20(6):447–454.
Global tuberculosis report 2021. Geneva: World Health Organization; 2021. Licence: CC BY-NC-SA 3.0 IGO.
Gutiérrez-González L.H., Juárez E., Carranza C., et. al Immunological Aspects of Diagnosis and Management of Childhood Tuberculosis. In: Infect Drug Resist 2021 Mar 8; 14:929-946.
Hunter, Robert L. (2020). The Pathogenesis of Tuberculosis. The Koch Phenomenon Reinstated. In: Pathogens, 9(10), 813.
Latent tuberculosis infection: updated and consolidated guidelines for programmatic management. Geneva: World Health Organization; 2018. Licence: CC BY-NCSA 3.0 IGO
Mangtani P., Abubakar I., Ariti C., Beynon R., Pimpin L., Fine P.E.M., et al. Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials. In: Clin Infect Dis (2014) 58(4):470–80.
Nowag, A., Hartmann, P. Immunität gegen Mycobacterium tuberculosis. In: Der Internist, 2016, 57(2), 107–116.
Padureanu L., Cozmei C., Carasevici E. Imunopatologia infecției tuberculoase. Disciplina de Imunologie, Facult. de Medicină, UMF Iasi, 2015, 40p.
Protocol clinic naţional „Tuberculoza la copil”, Chişinău, 2020, 180 p.
Protocol clinic naţional „Imunodeficiențele primare”, Chişinău, 2018, 54 p.
Roy R.B., Whittaker E., Kampmann B. Current understanding of the immune response to tuberculosis in children. In: Curr Opin Infect Dis. 2012; 14:250–257.
Tangye SG, Al-Herz W, Bousfiha A, Chatila T, Cunningham-Rundles C, Etzioni A, et al. Human inborn errors of immunity: 2019 update on the Classification from the International Union of Immunological Societies Expert Committee. In: J Clin Immunol. 2020;40(1):24–64.
van Coller A., Glanzmann B., Cornelissen H., et al. Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa. In: BMC Immunol. 2021; 22: 62.
Vanden Driessche K, Persson A, Marais BJ, Fink PJ, Urdahl KB. Immune Vulnerability of Infants to Tuberculosis. Clin Dev Immunol 2013; 2013:781320.
Vîlc V., Alexandru S., Crudu V., Ignat R. Controlul tuberculozei la nivelul asistenţei medicale primare. Ghid. Elaborat în cadrul proiectului „Fortificarea controlului tuberculozei în Moldova”, finanţat de către Fondul Global de combatere a SIDA, Tuberculozei şi Malariei. Chișinău, 2015, 97 p.
Корсунский И.А., Гордукова М.А., Мунблит Д.Б., Козлов И.Г., Продеус А.П., Корсунский А.А. Клинические и эпидемиологические аспекты первичных иммунодефицитных состояний и их раннего обнаружения. В: Медицинская иммунология. 2017;19(5):505-512.
Мордовская Л.И. Иммунодиагностика и иммунотерапия туберкулезной инфекции у детей и подростков. Автореферат, Москва, 2010, 220с.
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