Роль микробиома полости рта в диагностике и прогнозе опухолей полости рта
DOI:
https://doi.org/10.52692/1857-0011.2021.2-70.09Ключевые слова:
микробиом полости рта, биопленка, рак полости рта, воспаление, биомаркерАннотация
Роль микробиома полости рта в диагностике и прогнозировании опухолей полости рта (литературный обзор). Несмотря на прогресс в лечении опухолевых процессов, рак полости рта часто выявляется уже на запущенных стадиях. Последние достижения в метагеномных технологиях могут быть применены для идентификации микробиома, связанного с опухолями полости рта, включая рак ротовой полости, их геном, свойства вирулентности и их взаимодействие с иммунитетом хозяина. Модификация комменсальных микробных сообществ полости рта потенциально применима в качестве инструмента для диагностики и прогноза опухолей полости рта. Для разработки высокоточных и эффективных терапевтических подходов может потребоваться идентификация конкретных микробиомов полости рта. В данном обзоре мы сообщаем о роли микробиома в прогрессировании рака полости рта и его роли в качестве раннего и прогностического биомаркера опухолей полости ртаБиблиографические ссылки
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