В поисках идеального нейромышечного блокатора: обзор литературы

Авторы

  • Наталья Белый Universitatea de Stat de Medicină și Farmacie „N. Testemițanu”; Spitalul Republican pentru Copii „Em. Coțaga”

DOI:

https://doi.org/10.52692/1857-0011.2022.2-73.31

Ключевые слова:

миорелаксанты, индукция с быстрой последовательной интубацией, кура́ре

Аннотация

Техника современной общей анестезии является многокомпонентной, сбалансированной, с оротрахеальной интубацией, комбинируя препараты, воздействующие на различные рецепторы. Выбор оптимального миорелаксанта для особых обстоятельств в странах с низким доходом остаётся предметом дискуссий. Литературный обзор основан на публикациях в полном формате (n=14), опубликованных за последние 5 лет, отслеживая известные миорелаксанты, так и новые молекулы, испытанные в клинической практике, рассматривая их с точки зрения 10 фармакофизиологических характеристик идеального нервно-мышечного блокатора, а также через цепочку учёта контекстных клинических факторов. Достижения в этой области фармакологии особенно важны, но, похоже, их ещё следует ожидать.

Биография автора

Наталья Белый, Universitatea de Stat de Medicină și Farmacie „N. Testemițanu”; Spitalul Republican pentru Copii „Em. Coțaga”

dr. șt. med., asist. univer.; Catedra de anesteziologie și reanimatologie nr. 1 „V. Ghereg”

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Опубликован

2022-11-27

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