Sonographic changes of abdominal organs in children with different course of tuberculosis infection

Authors

  • Marina LOZOVSKAIA St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
  • Iulia POBEJIMOVA FBGU SPb GBUZ "DIB No. 3" of the Ministry of Health of the Russian Federation
  • Iulia IAROVAIA St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
  • Elena VASILIEVA St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
  • Liudmila KLOCHKOVA St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
  • Anna MOSINA FBGU SPb GBUZ "DIB No. 3" of the Ministry of Health of the Russian Federation
  • Irina EGOROVA FBGU SPb GBUZ "DIB No. 3" of the Ministry of Health of the Russian Federation

DOI:

https://doi.org/10.52692/1857-0011.2022.3-74.25

Keywords:

children, tuberculosis infection, ultrasound examination, abdominal organs

Abstract

In order to determine the frequency and nature of sonographic changes in abdominal organs in children with tuberculosis infection, 192 patients at the age of 6 months -14 years were examined on the basis of the tuberculosis department of City Children’s Infectious Hospital №3 for the period 2019-2021. 3 groups of patients were identified: group 1 - 92 children with active respiratory tuberculosis; group 2 – 52 children with residual post-tuberculosis changes; group 3 – 48 children with latent tuberculosis infection at risk of tuberculosis. Sonographic liver changes (reactive and/or intrahepatic cholestasis and/or hepatomegaly) were observed in children with active tuberculosis in 40.2±5.1% of cases, in children of group 3 - in 35.4±6.9% of cases and less often in children of group 2 - in 17.3±5.3% of cases (p<0.05). Changes of the gallbladder (violations of bile outflow and/or shape changes) were visualized in children with active tuberculosis in 73.9±4.6% of cases, in children of group 3 (60.4±7.1% of cases), less often in children of group 2 (55.8±6.7% of cases, p<0.05 for group 1). Changes of the pancreas were reactive and were more often observed in children of group 1 - in 14.1± 3.5% of cases than in children of group 2 (5.8±3.2% of cases, p<0.05) and group 3 (4.2± 2.9% of cases). Also, ultrasound changes of the spleen were more often detected in children with active tuberculosis - in 17.4±4.0% of cases than in children of group 2 (5.8±3.2% of cases, p<0.05) and group 3 (2.1±2.1% of cases, p<0.05).

Author Biographies

Marina LOZOVSKAIA, St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation

professor

Iulia POBEJIMOVA, FBGU SPb GBUZ "DIB No. 3" of the Ministry of Health of the Russian Federation

doctor

Iulia IAROVAIA, St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation

docent

Elena VASILIEVA, St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation

доцент

Liudmila KLOCHKOVA, St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation

docent

Anna MOSINA, FBGU SPb GBUZ "DIB No. 3" of the Ministry of Health of the Russian Federation

doctor

Irina EGOROVA, FBGU SPb GBUZ "DIB No. 3" of the Ministry of Health of the Russian Federation

doctor

References

Аксенова В.А., Гордина А.В., Стерликов С.А., Кудлай Д.А., Кучерявая Д.А., Докторова Н.П. Влияние активного выявления случаев туберкулеза на клини- ческую структуру и тяжесть туберкулеза у детей школьного возраста (7-15 лет). Туберкулез и болезни легких. 2022; 100 (1): 26-32.

Васильева И.А., Тестов В.В., Стерликов С.А. Эпидемическая ситуация по туберкулезу в годы пан- демии COVID-19 – 2020-2021 гг. Туберкулез и болезни легких. 2022;100(3): 6-12.

Зозуля М.Ю. Ультразвуковая диагностика аб- доминальных проявлений туберкулёзной инфекции у детей. Автореф. дис. на соиск. канд.мед.наук, СПб.; 2019.

Зозуля М.Ю., Воротынцева Н.С. Комплексная лучевая диагностика абдоминальных проявлений ту- беркулезной инфекции у детей. Курский научно-прак- тический вестник «Человек и его здоровье». 2016; № 3: 5-11.

Змитрович О.А. Ультразвуковая диагностика в цифрах: справочно-практическое руководство. 2 изд. СПб.: СпецЛит; 2014. 87 с.

Кривохиж В.Н., Степанов Г.А. Диагностика и лечение латентной туберкулезной инфекции (ЛТИ) у детей и подростков. Педиатр. 2017: 8 (S1): М166.

Ленский В.Е. Абдоминальный туберкулез: труд- ности диагностики. Сибирский медицинский журнал. 2006; №1: 4-10.

Логунова М.А., Егорова Д.С. Изменения орга- нов брюшной полости и почек, определяемые методом ультразвуковой диагностики у детей с туберкулезом органов дыхания. Forcipe. 2021; 4(S1): 934-935.

Мойдунова Н.К., Турдумамбетова Г.К. Ультраз- вуковая картина абдоминального туберкулеза. Меж- дународный журнал прикладных и фундаментальных исследований. 2017; № 6 (часть 1): 111-113.

Нечаева О.Б. Туберкулез у детей в России. Ту- беркулез и болезни легких 2020; 98(11): 12-20.

Правада Н.С., Будрицкий А.Н., Серегина В.А. Особенности выявления и диагностики туберкулеза у детей и подростков. Вестник Витебского государ- ственного медицинского университета. 2021; 20 (3): 40-45.

Савоненкова Л.В., Рузов В.И., Колчин Д.В., Арямкина О.Л., Скворцов В.В., Бессонов А.А. Трудно- сти и ошибки диагностики абдоминального туберку- леза в практике терапевта. Терапевтический архив. 2019; 91(11): 16-19.

Malik A., Saxena N.С. Ultrasound diagnos- ing abdominal tuberculosis. Аbdominal imaging. 2003; 28(4): 574-9. Available at: https://pubmed.ncbi.nlm.nih. gov/31565799/ (accessed 30.05.2022)

World Health Organization. Global tuberculosis report, 2021. Geneva: World Health Organization; 2021.

Published

2022-12-12

Issue

Section

Research Article

Categories