Эффективность терапии постоянным положительным давлением воздуха в дыхательных путях (СИПАП) у пациентов с апноэ во сне и резистентной артериальной гипертензией

Авторы

  • Олеся КОРШУН IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”
  • Анна КОТЕЛЯ IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”
  • Мария КОЧИУ IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”
  • Анна МОИСЕЕВА IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”
  • Александр КАРАУШ IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”

DOI:

https://doi.org/10.52692/1857-0011.2023.1-75.22

Ключевые слова:

телемониторинг, кардиореабилитация, телереабилитация

Аннотация

Терапия СИПАП приводит к снижению уровня артериального давления. При этом степень снижения уровня АД аналогична таковой, достигаемой некоторыми антигипертензивными препаратами, особенно у пациентов с резистентной гипертензией. Существует положительная и линейная корреляция между часами использования СИПАП и снижением уровня АД. СИПАП снижает как симпатическую активность, так и уровень концентрации альдостерона у пациентов с резистентной гипертензией и это может составлять некоторые патофизиологические механизмы действия, участвующие в этом лечении. Тем не менее, лечение и соблюдение режима СИПАП-терапии вместе с другими антигипертензивными препаратами значительно снижают и предотвращают высокое АД, сердечно-сосудистые заболевания и инсульт.

Биографии авторов

Олеся КОРШУН, IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”

cercetător științific

Анна КОТЕЛЯ, IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”

cercetător științific

Мария КОЧИУ, IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”

cercetător științific

Анна МОИСЕЕВА, IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”

dr. șt. med., cercetător științific

Александр КАРАУШ, IMSP Institutul de Cardiologie, Clinica “Hipertensiuni arteriale”

dr. hab. șt. med., profesor cercetător

Библиографические ссылки

Baguet JP, Barone-Rochette G, Pépin JL. Hypertension and obstructive sleep apnoea syndrome: current perspectives. J Hum Hypertens. 2009;23(7):431–443. [PubMed] [Google Scholar] [Ref list]

Marcus Jonathan A, Pothineni Aravind, Marcus Carolina Z, et al. The role of obesity and obstructive sleep apnea in the pathogenesis and treatment of resistant hypertension. Curr Hypertens Rep. 2014;16(1):411. [PubMed] [Google Scholar]

Gilardini L, Lombardi C, Redaelli G, et al. Effect of continuous positive airway pressure in hypertensive patients with obstructive sleep apnea and high urinary metanephrines. J Hypertens. 2018;36(1):199–204. [PubMed] [Google Scholar] [Ref list]

Kato M, Roberts-Thomson P, Phillips BG, et al. Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apnea. Circulation. 2000;102(21):2607–2610. [PubMed] [Google Scholar] [Ref list]

Pinto P, Barbara C, Montserrat JM, et al. Effects of CPAP on nitrate and norepinephrine levels in severe and mild-moderate sleep apnea. BMC Pulm Med. 2013;13:13. [PMC free article] [PubMed] [Google Scholar] [Ref list]

Behan M, Wenninger JM. Sex steroidal hormones and respiratory control. Respir Physiol Neurobiol. 2008;164:213–21. [PMC free article] [PubMed] [Google Scholar] [Ref list]

Shahar E, Redline S, Young T, et al. Hormone replacement therapy and sleep-disordered breathing. Am J Respir Crit Care Med. 2003;167:1186–92. [PubMed] [Google Scholar] [Ref list]

Meta-analysis of effects of obstructive sleep apnea on the renin-angiotensin-aldosterone system. Jin Z-N, Wei Y-X. https://www.ncbi.nlm.nih.gov/pubmed/27403143. J Geriatr Cardiol. 2016;13:333–343. [PMC free article] [PubMed] [Google Scholar] [Ref list]

Shrout Tara, David W Rudy, Michael T Piascik. Hypertension update, JNC8 and beyond. Curr Opin Pharmacol. 2017;33:41–46. [PubMed] [Google Scholar]

Martínez-García M.A., Capote F., Campos-Rodríguez F., Lloberes P., Díaz de Atauri M.J., Somoza M., Masa J.F., González M., Sacristán L., Barbé F., et al. Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: The HIPARCO randomized clinical trial. JAMA. 2013;310:2407–2415. doi: 10.1001/jama.2013.281250. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Lozano L., Tovar J.L., Sampol G., Romero O., Jurado M.J., Segarra A., Espinel E., Río J., Untoria M.D., Lloberes P. Continuous positive airway pressure treatment in sleep apnea patients with resistant hypertension: A randomized, controlled trial. J. Hypertens. 2010;28:2161– 2168. doi: 10.1097/HJH.0b013e32833b9c63. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Ishida K, Kato M, Kato Y, et al. Appropriate use of nasal continuous positive airway pressure decreases elevated c-reactive protein in patients with obstructive sleep apnea. Chest. 2009;136(1):125–129. [PMC free article] [PubMed] [Google Scholar] [Ref list]

Haentjens P, Van Meerhaeghe A, Moscariello A, et al. The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials. Arch Intern Med. 2007;167(8):757– 764. [PubMed] [Google Scholar] [Ref list]

Pepperell JC, Ramdassingh-Dow S, Crosthwaite N, et al. Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial. Lancet. 2002;359(9302):204–210. [PubMed] [Google Scholar] [Ref list]

Lloberes P., Sampol G., Espinel E., Segarra A., Ramon M.A., Romero O., Ferrer R., Martínez-Garcia M.A., Tovar J.L. A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea. J. Hypertens. 2014;32:1650–1657. doi: 10.1097/HJH.0000000000000238. [PubMed] [CrossRef] [Google Scholar] [Ref list]

de Souza F., Muxfeldt E.S., Margallo V., Cortez A.F., Cavalcanti A.H., Salles G.F. Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: A randomized controlled trial. J. Hypertens. 2017;35:837–844. doi: 10.1097/JH.0000000000001254. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Joyeux-Faure M., Baguet J.P., Barone-Rochette G., Faure P., Sosner P., Mounier-Vehier C., Lévy P., Tamisier R., Pépin J.L. Continuous Positive Airway Pressure Reduces Night-Time Blood Pressure and Heart Rate in Patients with Obstructive Sleep Apnea and Resistant Hypertension: The RHOOSAS Randomized Controlled Trial. Front. Neurol. 2018;9:318. doi: 10.3389/fneur.2018.00318. [PMC free article] [PubMed] [CrossRef] [Google Scholar] [Ref list]

Lei Q., Lv Y., Li K., Ma L., Du G., Xiang Y., Li X. Effects of continuous positive airway pressure on blood pressure in patients with resistant hypertension and obstructive sleep apnea: A systematic review and meta-analysis of six randomized controlled trials. J. Bras. Pneumol. 2017;43:373–379. doi: 10.1590/s180637562016000000190. [PMC free article] [PubMed] [CrossRef] [Google Scholar] [Ref list]

Ohike Y, Kozaki K, Iijima K, et al. Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine. Circ J. 2005;69(2):221–226. [PubMed] [Google Scholar] [Ref list]

de Souza F., Muxfeldt E.S., Margallo V., Cortez A.F., Cavalcanti A.H., Salles G.F. Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: A randomized controlled trial. J. Hypertens. 2017;35:837–844. doi: 10.1097/JH.0000000000001254. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Linz D., Mancia G., Mahfoud F., Narkiewicz K., Ruilope L., Schlaich M., Kindermann I., Schmieder R.E., Ewen S., Williams B., et al. Renal artery denervation for treatment of patients with self-reported obstructive sleep apnea and resistant hypertension: Results from the Global SYMPLICITY Registry. J. Hypertens. 2017;35:148–153. doi: 10.1097HJH.0000000000001142. [PubMed] [CrossRef] [Google Scholar] [Ref list].

Campos-Rodriguez F., Navarro-Soriano C., ReyesNuñez N., Torres G., Caballero-Eraso C., Lloberes P., Diaz-Cambriles T., Somoza M., Masa J.F., Gonzalez M., et al. Good long-term adherence to continuous positive airway pressure therapy in patients with resistant hypertension and sleep apnea. J. Sleep Res. 2019;28:e12805. doi: 10.1111/jsr.12805. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Navarro-Soriano C., Martínez-García M.A., Torres G., Barbé F., Caballero-Eraso C., Lloberes P., Diaz Cambriles T., Somoza M., Masa J.F., González M., et al. Effect of continuous positive airway pressure in patients with true refractory hypertension and sleep apnea: A post-hoc intention-to-treat analysis of the HIPARCO randomized clinical trial. J. Hypertens. 2019;37:1269–1275. doi: 10.1097/JH.0000000000002053. [PubMed] [CrossRef] [Google Scholar] [Ref list]

Navarro-Soriano C., Martínez-García M.A., Torres G., Barbé F., Caballero-Eraso C., Lloberes P., Cambriles T.D., Somoza M., Masa J.F., González M., et al. Factors associated with the changes from a resistant to a refractory phenotype in hypertensive patients: A Pragmatic Longitudinal Study. Hypertens. Res. 2019;42:1708–1715. doi:10.1038/s41440-019-0285-8. [PubMed] [CrossRef] [Google Scholar]

Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013;177(9):1006–14. https://doi.org/10.1093/aje/kws342.

Teramoto S, Kume H, Matsuse T, et al. Oxygen administration improves the serum level of nitric oxide metabolites in patients with obstructive sleep apnea syndrome. Sleep Med. 2003;4(5):403–407. [PubMed] [Google Scholar] [Ref list]

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Опубликован

2023-06-01

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Научная статья

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