Неврологические осложнения после инфекции Ковид-19
DOI:
https://doi.org/10.52692/1857-0011.2024.3-80.10Ключевые слова:
КОВИД-19, неврологические осложнения, головная боль, синдром Гийена-Барре, когнитивные расстройстваАннотация
Вирус Sars-CoV-2 относится к группе коронавирусов, обладающих способностью поражать несколько систем, таких как дыхательная, сердечно-сосудистая, почечная, желудочно-кишечная. Особая роль принадлежит нервной системе, эта инфекция затрагивает центральную нервную систему (ЦНС) и периферическую нервную систему (ПНС). Основными путями передачи вируса являются периферический, гематогенный и лимфатический пути. Ангиотензинконвертаза 2 (АПФ2) играет существенную роль в патогенезе КОВИД-19, лежит в основе воспалительных механизмов и так называемых «цитокиновых штормов», влияющих на развитие коагулопатий и последующих осложнений, при вирусной инвазии мозговой ткани за счет пересечения гематоэнцефалического барьера. В статье проанализированы основные пути вирусной инвазии, а также развивающиеся неврологические осложнения, затрагивающие как центральную, так и периферическую нервную систему.
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