Essential tremor- diagnostic criteria and treatment modalities.

Authors

  • Olga GAVRILIUC Scientific laboratory of Functional Neurology Institute of Neurology; Neurosurgery "Diomid Gherman"
  • Paula FALA Department of Neurology State University of Medicine and pharmacy "Nicolae Testemitanu"
  • Mihail GAVRILIUC Department of Neurology State University of Medicine and pharmacy "Nicolae Testemitanu"
  • Alexandru ANDRUSHKA "Nicolae Testemitanu" State University of Medicine and Pharmacy

DOI:

https://doi.org/10.52692/1857-0011.2021.3-71.24

Keywords:

movement disorders, essential tremor, propranolol

Abstract

Essential tremor (EЕ) is the most common cause of action tremor in adults. In most cases, TE can be managed by primary care physicians, starting with the exclusion of secondary causes and followed by initiation of propranolol or primidone therapy if the tremor causes disability. The decision to refer a neurologist depends on the clinician’s confidence in the diagnosis, his or her level of comfort with the use of medications recommended for tremor suppression, and the patient’s response to treatment.

References

Benito-León J, Bermejo-Pareja F, Morales JM, et al. Prevalence of essential tremor in three elderly populations of central Spain. Mov Disord 2003; 18:389.

Louis ED, Ferreira JJ. How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord 2010; 25:534.

Louis ED. ‘Essential tremor’ or ‘the essential tremors’: is this one disease or a family of diseases? Neuroepidemiology 2014; 42:81.

Hopfner F, Haubenberger D, Galpern WR, et al. Knowledge gaps and research recommendations for essential tremor. Parkinsonism Relat Disord 2016; 33:27.

Jasinska-Myga B, Wider C. Genetics of essential tremor. Parkinsonism Relat Disord 2012; 18 Suppl 1:S138.

Louis ED, Faust PL, Vonsattel JP, et al. Neuropathological changes in essential tremor: 33 cases compared with 21 controls. Brain 2007; 130:3297.

Louis ED, Babij R, Lee M, et al. Quantification of cerebellar hemispheric purkinje cell linear density: 32 ET cases versus 16 controls. Mov Disord 2013; 28:1854. Științe Medicale 29

Cerasa A, Quattrone A. Linking Essential Tremor to the Cerebellum-Neuroimaging Evidence. Cerebellum 2016; 15:263.

Bhatia KP, Bain P, Bajaj N, et al. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Mov Disord 2018; 33:75.

Louis ED, Bares M, Benito-Leon J, et al. Essential tremor-plus: a controversial new concept. Lancet Neurol 2020; 19:266.

Benito-León J, Louis ED, Sánchez-Ferro Á, Bermejo-Pareja F. Rate of cognitive decline during the premotor phase of essential tremor: a prospective study. Neurology 2013; 81:60.

Pahwa R, Koller WC. Is there a relationship between Parkinson’s disease and essential tremor? Clin Neuropharmacol 1993; 16:30.

Agnew A, Frucht SJ, Louis ED. Supine head tremor: a clinical comparison of essential tremor and spasmodic torticollis patients. J Neurol Neurosurg Psychiatry 2012; 83:179.

Haubenberger D, Hallett M. Essential Tremor. N Engl J Med 2018; 378:1802.

Zesiewicz TA, Elble R, Louis ED, et al. Practice parameter: therapies for essential tremor: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2005; 64:2008.

Rajput AH, Rajput A. Medical treatment of essential tremor. J Cent Nerv Syst Dis 2014; 6:29.

Bhatia KP, Bain P, Bajaj N, et al. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Mov Disord 2018; 33:75.

Thenganatt MA, Louis ED. Distinguishing essential tremor from Parkinson’s disease: bedside tests and laboratory evaluations. Expert Rev Neurother 2012; 12:687.

Louis ED, Bares M, Benito-Leon J, et al. Essential tremor-plus: a controversial new concept. Lancet Neurol 2020; 19:266.

Gasparini M, Bonifati V, Fabrizio E, et al. Frontal lobe dysfunction in essential tremor: a preliminary study. J Neurol 2001; 248:399.

Benito-León J, Louis ED, Sánchez-Ferro Á, Bermejo-Pareja F. Rate of cognitive decline during the premotor phase of essential tremor: a prospective study. Neurology 2013; 81:60.

Zesiewicz TA, Elble RJ, Louis ED, et al. Evidence-based guideline update: treatment of essential tremor:report of the Quality Standards subcommittee of the American Academy of Neurology. Neurology 2011; 77:1752.

Deuschl G, Raethjen J, Hellriegel H, Elble R. Treatment of patients with essential tremor. Lancet Neurol 2011; 10:148.

Elias WJ, Shah BB. Tremor. JAMA 2014; 311:948.

Nida A, Alston J, Schweinfurth J. Primidone Therapy for Essential Vocal Tremor. JAMA Otolaryngol Head Neck Surg 2016; 142:117.

Zappia M, Albanese A, Bruno E, et al. Treatment of essential tremor: a systematic review of evidence and recommendations from the Italian Movement Disorders Association. J Neurol 2013; 260:714.

Gironell A, Kulisevsky J, Barbanoj M, et al. A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor. Arch Neurol 1999; 56:475.

Published

2021-11-17

Issue

Section

Research Article