The circadian rhythm and sleep disorders in pregnant women

Authors

  • Dumitritsa CAZAC-STAMATI Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”
  • Lilia ROTARU Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Oxana GROSU Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Stela ODOBESCU Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Svetlana LOZOVANU Universitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”
  • Adrian LUPUSHOR "Nicolae Testemițanu" State University of Medicine and Pharmacy; Institute of Neurology and Neurosurgery "Diomid Gherman"
  • Ion STAMATI "Nicolae Testemițanu" State University of Medicine and Pharmacy

DOI:

https://doi.org/10.52692/1857-0011.2022.3-74.02

Keywords:

circadian clock, circadian disruption , chronotherapy, pregnancy, sleep

Abstract

The circadian rhythm is an endogenous process that has a periodicity of approximately 24 hours and stimulates the
anticipation of repeated and regular events that occur daily, enabling the regulation of most major physiological systems
in humans and animals. Thus, studies have shown that disruption of circadian rhythm and sleep is a frequent cause of a
series of pathologies for the general population, including pregnant women and their fetus. The purpose of this article is
to review the literature on the relationship between circadian rhythm and sleep disorders in pregnant women and the influence on the development of the fetus, as well as the future developing adult. Pregnancy is a critical peiod in which the
systems of organs of a new human body are developing, and any disturbance in the environment in which the fetus grows
can lead to developmental disorders that alter the metabolic and physiological functions of the fetus. Thus, maintaining an
undisturbed circadian rhythm, including during pregnancy, protects the health of both the mother and the child, reducing
the susceptibility to the development of certain postnatal diseases later in life.

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Published

2022-12-12

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Research Article

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